Key Takeaway: The use of clopidogrel plus aspirin compared with aspirin alone reduced the risk of a new stroke only in patients with normal CYP2C19 activity. This supports the findings that CYP2C19 genotype has a role in the efficacy of this treatment. Each year, approximately 795,000 people in the United States suffer a stroke and antiplatelet therapy plays a critical … Read More
This Month in Pharmacogenetics
Pharmacogenomics and Precision Medicine is trending like never before, with the strides that are being made in this field. While you can go and search out the news yourself, we want to make it easy for you. You can start by following social media platforms: YouScript Facebook, YouScript Twitter, Pinterest, LinkedIn, and our partner sites Genelex Facebook and Genelex Twitter. … Read More
Updated Phenotype Terminology
YouScript and Genelex Labs have updated their phenotype names to be consistent with the standardized terms for clinical pharmacogenetic test results proposed by the Clinical Pharmacogenetics Implementation Consortium (CPIC) in the July 2016 issue of Genetics in Medicine. Like CPIC, we believe that implementing standardized terminology is an important step toward the widespread adoption of clinical pharmacogenetics. These standard terms … Read More
CYP2D6 Testing Could Ease Parents Fears After Codeine Warning
A recent warning from the American Academy of Pediatrics has many parents worrying if their child is an ultrarapid metabolizer of the popular drug codeine. The clinical report is calling for a formal restriction of codeine, over risks of life-threatening or fatal breathing reactions. The pain reliever is often given in hospitals for procedures such as tonsillectomies and is commonly … Read More
The Value of Usability Engineering in Clinical Decision Support Tools
National Health IT Week celebrates the power of Health Information Technology to improve the health and healthcare of patients across the nation. The advantages and disadvantages of technology such as Electronic Health Record (EHR) systems have been discussed since 2009 with the passage of the Health Information Technology for Economic and Clinical Health (HITECH) Act. Similarly, Clinical Decision Support Systems … Read More
This Month in Pharmacogenetics
We’re back again with another round of PGx Articles. Pharmacogenomics is on the rise, and with the groundswell of support we’re seeing, it’s only a matter of time before we see more widespread support and implementation. Want to be ahead of the curve? Want to be that person who says “remember when I told you about pharmacogenetics years ago” to … Read More
Visit us at EPIC UGM 2016 September 19th-22nd
Please come visit us at EPIC User Group Meeting 2016 September 19th through 22nd in Madison Wisconsin. Earlier this year YouScript and Epic announced a partnership to integrate YouScript into Epic’s EMR system in an effort to save lives and reduce costs. Please stop by our booth to learn how YouScript can work for you! Please check our twitter feed for updates … Read More
Is Big Data Clinically Significant?
A restaurant patron doesn’t leave a tip as he storms out of the trashy diner that Google “recommended” to him. This is an example of big data trying to predict what kind of restaurants that customer might enjoy, and missing the mark entirely. Nevertheless, the consequences of this blunder are mild, maybe resulting in an upset stomach or a dented … Read More
This Month in Pharmacogenomics
While we here at YouScript are in the business of promoting our business, and the benefits of PGx, and the importance of being able to make those results actionable for patients and providers with the YouScript Clinical Decision Tool, we also care very much about the promotion of PGx as a whole. And with our many social media platforms, YouScript … Read More
Unexpected Culprit – Is Grapefruit Affecting Your Drug Regimen?
In January of this year, we wrote about how herbal and dietary supplements can alter the metabolism of certain medications. St. John’s Wort was the supplement primarily discussed. However, it is not just herbal supplements that can alter drug metabolism and cause drug interactions; food can be a common offender as well. This week we will be looking at the … Read More