Use of pharmacogenetic testing supported by an appropriate clinical decision support tool reduces mortality and overall health resource utilization in patients treated with multiple medications Seattle, WA — YouScript, a proprietary clinical decision support tool designed to assist in medication therapy management, has been shown to reduce readmissions by 52 percent (p=0.007) and ER visits by 42 percent (p=0.045) in … Read More
PSYCHIATRIC PHARMACOGENETICS from concepts to cases Book Now Available
Clinicians who treat psychiatric patients know that medications can be lifesaving, but they also know that these same potentially lifesaving psychotropic medications can have serious side effects. We now have a tool in pharmacogenetic testing that can help minimize medication side effects. Patients are increasingly requesting that their provider use this tool to help more accurately select a treatment, address … Read More
Updated Phenotype Terminology
YouScript and Genelex Labs have updated their phenotype names to be consistent with the standardized terms for clinical pharmacogenetic test results proposed by the Clinical Pharmacogenetics Implementation Consortium (CPIC) in the July 2016 issue of Genetics in Medicine. Like CPIC, we believe that implementing standardized terminology is an important step toward the widespread adoption of clinical pharmacogenetics. These standard terms … Read More
CYP2D6 Testing Could Ease Parents Fears After Codeine Warning
A recent warning from the American Academy of Pediatrics has many parents worrying if their child is an ultrarapid metabolizer of the popular drug codeine. The clinical report is calling for a formal restriction of codeine, over risks of life-threatening or fatal breathing reactions. The pain reliever is often given in hospitals for procedures such as tonsillectomies and is commonly … Read More
Precision Trials Challenge – LINK, please comment or like
Big thanks to Ranjit who submitted to this challenge with little notice, description is below. Comments from the online community will also be used as judging criteria. So any responses via comments/applause/views via the link below with respect to this idea’s innovation, impact and feasibility (a simple login using your existing Google or Facebook account is required) are appreciated. The … Read More
New research shows YouScript cuts ER visits, hospitalizations
What if an under-used type of genetic testing combined with state-of-the-art clinical decision support software could cut ER visits by more than half and reduce hospitalizations by a third in the elderly? New research has found that the YouScript Personalized Prescribing System, combining pharmacogenetic testing and patented medication management software, can do just that. Preliminary data from a soon-to-be-published study … Read More
New financial analysis reveals significant savings realized from CYP2C19 testing
Twenty lives and $440,000 over a year. For every 1,000 patients. That’s what CYP2C19 pharmacogenetic testing could save if used to help prescribe clopidogrel (Plavix), prasugrel or ticagrelor to specific cardiac patients. A budget analysis found that a genotype-guided approach for acute coronary syndrome patients (ACS) undergoing percutaneous coronary intervention (PCI) for one year saved 20 lives and $444,852 in … Read More
Mapping the human placebome? Genetics may hold key to placebo effect
Could the reason why the placebo effect works for some people and not others lie in their DNA? The authors of a new scientific review article make the case that, just as an individual’s response to medications is dependent upon their unique genetics, so too could their response to placebos. In the article, authors Hall, Loscalzo and Kaptchuk delve into … Read More
Genelex-sponsored research awarded at managed care pharmacy conference
Recent research sponsored by Genelex and undertaken by University of Utah researchers has been recognized at the national Academy of Managed Care Pharmacy (AMCP) conference. The research shows that as many as 50 percent of patients 65 and older are taking at least one medication metabolized by a genetically variable drug metabolizing enzyme. The poster for this work, co-presented by Genelex … Read More
Research reveals significant impact of drug-gene and drug-drug-gene interactions
Why do some patients react differently to the same drug? A study using data analyzed by the YouScript Personalized Prescribing Software has quantified the role genotypes may play in causing adverse drug reactions. The research, published in the journal Pharmacogenomics, showed that a combined 33.9 percent of all potential clinically significant drug interactions were due to drug-gene and drug-drug-gene interactions. These potential … Read More
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