Large study links DPYD genetic variations and toxicity of cancer drug

The association between variants of the DPYD gene and serious side effects from the cancer drug 5-fluorouracil (5–FU) in colon cancer patients has been bolstered by the results of recent large-scale study. The largest study to date investigating the association between DPYD variants and 5-FU adverse drug events has found a statistically significant association between two variants that decrease DPYD … Read More