By Rachel Sass, PharmD Should providers increase the clopidogrel dose in patients with decreased functioning CYP2C19 enzymes? Clopidogrel (Plavix) is one of the most well studied medications in pharmacogenetics. Clopidogrel is a prodrug, meaning that it needs to be converted to an active metabolite in the body to have an effect. This metabolizing process occurs in part via the polymorphic … Read More