Study shows 50% drop in serious bleeding with DNA-guided warfarin treatment

A new meta-analysis of clinical trials scrutinizing warfarin dosing methods found that warfarin treatment guided by individual genotypes reduced instances of serious bleeding by more than half compared to standard dosing approaches. The work lends support to the importance of genetic testing for the genes CYP2C9 and VKORC1, variations of which can influence warfarin’s therapeutic effect. In August 2007, the U.S. … Read More