The mental deterioration of a 33-year-old man with HIV began with vivid dreams just weeks after he began a standard course of HIV treatment. The treatment was a combination of the medications efavirenz, tenofovir and emtricitabine (Atripla). This course seemed successful, with the man’s HIV viral load decreasing to non-detectable levels within a few weeks. HIV treatment continued. Then the … Read More
Study strengthens link between gene variants and bleeding risk in warfarin patients
New research offers more evidence for the connection between CYP2C9 and VKORC1 variants and increased bleeding risk in patients taking warfarin. A large-scale study published in the March edition of the Lancet found that atrial fibrillation patients whose CYP2C9 and VKORC1 genetic variations made them highly sensitive to warfarin were nearly three times more likely to experience bleeding than those … Read More
Flawed studies informed recommendations against CYP2D6 testing for tamoxifen treatment, new study finds
A recent Mayo Clinic study has found that clinical recommendations discouraging the use of CYP2D6 genetic testing to advise tamoxifen treatment in women with breast cancer should be reconsidered because some of the studies the recommendations were based on had flawed methodology. The article, published in the January issue of the Journal of the National Cancer Institute, found that some … Read More
Raising awareness of diabetes in November
November is diabetes awareness month in the U.S., a time to learn more about a disease that affects an estimated 30 million American children and adults. According to data from the Centers for Disease Control and Prevention (CDC), the number of adults with diabetes nearly tripled between 1980 and 2011, going from 5.6 million people to 20.9 million. The American … Read More
Study: 32 percent of people with cancer have anxiety or other mental health disorder
A recent study has found that just more than 30 percent of people with cancer in Germany also experienced some form of clinically relevant mental health disorder. The article, published earlier this month in the Journal of Clinical Oncology, found that 32 percent of people with cancer, or about one in three, had also experienced a clinically meaningful level of … Read More
Study finds opioid use common amongst disabled Medicare recipients
A recent study illuminates the prevalence of opioid painkiller use in a particularly vulnerable population: disabled Americans on Social Security disability insurance. The article, published in the September edition of the journal Medical Care, found the percentage of Social Security disability insurance (SSDI) recipients younger than 65 receiving any amount of opioid prescriptions rose from 43.9 percent in 2007 to … Read More
Study: Elderly patients at greater risk of kidney injury if on antipsychotic drugs
New research into the risks of three common antipsychotic drugs for the elderly suggests older patients are 73 percent more likely to experience acute kidney injury (AKI) while on any of the three medications. The research, published in the August 19 issue of the Annals of Internal Medicine, examined the medical records of nearly 100,000 adults 65 and older who … Read More
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