YouScript® and Genelex In the News
Genelex Honored Among Fastest-growing Private Companies in 2013
September 11, 2013
Puget Sound Business Journal
After a record-breaking time of expansion, Genelex makes Puget Sound Business Journal's prestigious list of top 100 fastest-growing private companies in 2013.
YouScript® on KOMO News Radio
September 12, 2012
Howard Coleman and Kristine Ashcraft talk to Jane Shannon, of KOMO News Radio, about the YouScript® Personalized Prescribing System.
Seattle Company Using DNA Tests to Personalize Medicine
September 12, 2012
KOMO - Molly Shen - A local company has a new approach to personalized medicine: getting your prescription drugs based on your DNA. Read the article and watch the TV spot.
Cytochrome P450 Testing: In High-dose Opioid Patients
Practical Pain Management Journal - Dr. Forest Tennant - Severe, chronic pain patients who seek opioid dosages above normal standards should now be tested for genetic cytochrome P450 deficiencies. - Available in the August 2012 issue. Subscription required.
The Worldwide Market for In Vitro Diagnostic (IVD) Tests, 8th Edition
Kalorama - The Worldwide Market for In Vitro Diagnostic Tests, is a testament to the Kalorama methodology. Real industry knowledge combined with an exhaustive review of the medical, business, and company literature. Market numbers for business planning matched with a discovery of the trends that are impacting the industry. A realistic forecast five years into the future for companies already participating in or considering entry into this growing industry.
Consumer Testing and the Future of DTC Genetic Testing
Kalorama - In February and March of 2012, Kalorama Information conducted a survey of 2,000 adults to ask them whether or not they would take a genetic test. This report, Consumer Testing and the Future of DTC Genetic Testing provides those results and compiles surveys from public and private sources.
World Market for Personalized Medicine Diagnostics (Biomarkers, Pharmacodiagnostics, Tumor Assays, Cardiac Risk and Other Testing)
Kalorama - In this market research report, Kalorama Information defines the current opportunity and a realistic future potential for personalized medicine in clinical testing. In addition to analysis of tests currently on the market and in development, the report profiles key competitors and discusses trends that are important for understanding this much-discussed growth area of the diagnostic industry.
Most doctors are behind the learning curve on genetic tests
October 24, 2010
USA Today - Rita Rubin - Since the Human Genome Project was completed in 2003, the introduction of new genetic tests has far outpaced the ability of doctors — who typically have little training in genetics — to figure out what to do with them. Some tests are marketed to help predict disease risk, others to determine how patients might respond to certain medications.
Quest, Fattening Molecular Play, to Debut Spit-Based Plavix-Response Test This Month
October 9, 2009
Genome Web - Kirell Lakhman - Quest Diagnostics later this month plans to offer nationwide a PCR-based assay designed to predict response to the anticoagulant Plavix. According to genetic-testing company Genelex, which is among several shops offering similar assays, “most” of the approximately 1 million patients who undergo coronary stent procedures each year in the US are prescribed Plavix. Those that carry mutated versions of the CYP2C19 gene will not likely respond well to the drug, which puts them at greater risk for adverse cardio- and neurovascular events.
Dr PC will see you now
February 2, 2009
Computer Act!ve - Jon Thompson - In recent years, an unprecedented explosion in personal technology has transformed how we live and work. Now the same is happening to healthcare. In labs across the world, the blind are seeing again for the first time in years, the disabled are beginning to walk again, and everything from wheelchairs to robotic limbs are being controlled by thought alone.
New DNA Test Identifies Important Enzyme
October 8, 2008
Q13Fox.com - Lara Yamada - Chances are you haven't heard of an enzyme called "CYP-2D6." 200,000 men and women are diagnosed with breast cancer every year and 40,000 die. One reason is the lack of that enzyme--which can stand between you and your treatment. There is a simple test that can save your life-and thousands of others.
A Roadmap to Diagnostics in the 21st Century
Sep 10, 2008
MarketWatch - Learn about the Diagnostic Test Service Commercialization in Multiplex and Esoteric Testing
Howard Coleman on Warfarin
August 28, 2008
XConomy.com - Gregory T. Huang - Update on how the federal Centers for Medicare & Medicaid Services has taken up the question of whether to pay for DNA tests to help determine a personalized dose for the common blood-thinning drug, Warfarin.
Testing Services Markets, SNP Analysis, DNA Sequencing, Retail Clinics, Companion Diagnostics
Kalorama - A bundle of five Kalorama Information reports, this resource, representing over 1,000 pages of information on cutting-edge topics critical to the future of diagnostics.
Diagnostic Test Service Commercialization in Multiplex and Esoteric Testing: A Roadmap to Diagnostics in the 21st Century
Kalorama - Test services, once the norm in the diagnostics industry, then abandoned for reagent sales, are now making a comeback.
IVD companies have established cGMP and CLIA-registered labs by which they offer their proprietary tests to physicians, hospitals and reference labs. These tests are outside the oversight of the traditional FDA and CE Mark test commercialization avenue in the U.S, and Europe and so are thought to come to market by what may seem to be the back door.
Policy Paper Calls for More Pharmacogenetic Oversight
April 3, 2008
GenomeWeb Daily News - Andrea Anderson - Genelex CEO Howard Coleman issued a statement today maintaining that the company’s web site was quoted out of context and reaffirming the company’s belief that individuals should have the right to learn and control information about their genotype.
DNA Tests a Mouse Click Away
March 28, 2008
Toronto Star - Nancy J. White - Another area of huge promise is pharmacogenomics, the interplay between genes and drugs. For some Internet companies, drug response tests are already popular sellers. Genelex, a web-based Seattle firm, offers screening for five genes that it maintains will help a doctor predict response to many drugs.
Who’s the father? Find out in a jiffy with DNA paternity test
March 26, 2008
Philadelphia Inquirer - Faye Flam and Tom Avril - The problem with drugstore testing is that there's no proof that the DNA samples came from the people claimed to have sent them. Therefore, such results
wouldn't hold up legally.
Could your DNA hold the key to a wrinkle-free face and a great figure?
June 19, 2007
Daily Mail – Claire Colman - Developments in health and beauty focus on examining your DNA, the unique building blocks of your body, to come up with a lifestyle, diet and beauty plan designed exclusively for you.
Personal genetic tests: genius or bogus?
April 26, 2007
Globe and Mail - Hayley Mick - When Kathy Dyck's weight ballooned to a lifetime high of 250 pounds, she ditched her usual weight-loss tricks: Atkins and other commercial diets. Instead, Ms. Dyck, who lives on Vancouver Island, turned to the Internet and discovered a new and rapidly growing genre of personalized health products -- diets tailored to genetic makeup.
Deciphering Daddy's DNA
March 4, 2007
US News and World Report - Nancy Shute - Genetic advances have improved paternity tests. Howard Coleman, CEO of Genelex, a genetics-testing lab in Seattle. "Anything that someone's had contact with ... and we can give you a very conclusive answer."
Days Before Warfarin Label Change, Genelex Debuts DTC Dosing Dx; ASHG's 'Validity' Notice Could Help
October 18, 2006
Pharmacogenomics Reporter - Kirell Lakhman - Genelex, the direct-to-consumer genetic testing shop, rolled out a warfarin dosing product earlier this month, three days before US regulators and Bristol-Myers Squibb added a black box warning to the label of the ubiquitous anticoagulant, marketed by BMS under the trade name Coumadin.
DNA test for Coumadin gives dosage
Oct. 9, 2006
Consumer Health Daily - U.S. patients who take the blood thinner Coumadin, or warfarin, will soon notice a new Food and Drug Administration label attached to their prescription.
New test helps pinpoint dosage for blood thinner
September 29, 2006
KING 5 News - Lori Matsukawa - While too late for him, Krafchick says the test will spare the estimated 300,000 people in the U.S. who begin taking Coumadin every year from weeks of uncertainty.
The Gene Screen
October 3, 2006
CNNMoney.com – Jennifer Alsever - For instance, Jenifer Mansell of Homer Glen, Ill., ordered a pharmacogenetic test from Seattle's Genelex when a prescribed medication didn't seem to help her 3-year-old son after a series of heart surgeries.
US Turning to DNA to Prove Family Ties
August 24, 2006
Seattle Times - Lornet Turnbull - After waiting nearly 12 years to help his sister and her family obtain green cards so they could move to the U.S., Nak Sieng faced one final hurdle: proving he and his sister really are related.
DNA testing more common for immigration applications
July 28, 2006
Daily Herald – Peter Prengaman - Bradley Waite wanted to bring his adult daughter to this country from Jamaica, but couldn't prove they were related – she was born out of wedlock, so his name was not on her original birth certificate. U.S. immigration officials did something that is unusual but becoming more common: They asked for DNA tests.
DNA Testing Increases in Immigration Cases
June 26, 2006
Los Angeles Times - Anna Gorman - When Scarlett Simonian petitioned in 2004 for her Honduran mother to immigrate to the U.S., she was asked to provide a birth certificate and other documents to prove they were blood relatives. But recently Simonian was told she needed more proof. The consular officer in Honduras suggested a DNA test.
Gene Screens Promise Nutrition Insights
May 7, 2006
Forbes - Feeling listless? Losing the fight against obesity? Genetic data locked inside a few cheek cells could help explain why -- and maybe even help you turn things around.
Liver Success Emerging Enzyme Test Can Predict Drug Side Effects.
April 18, 2006
Washington Post - Lisa Barrett Mann - Adverse drug reactions -- what most of us call side effects -- can range from annoying (headaches) to debilitating (diarrhea, vomiting) to deadly. And certain drugs – especially psychiatric and cardiac ones -- are more apt to cause severe reactions. If only doctors had a way to predict who's most susceptible.
This just in: Eat your vegetables: A reporter's personal genome project
January 03, 2006
Canada.com - Michael Friscolanti - With a swab of saliva and a swipe of a credit card, countless health-conscious consumers are paying top dollar to discover what microscopic evils lurk in their genes.
New Web Site Helps Prevent Medicine Mix-Ups
Dec 1, 2005
KOMO Health Watch - Leslie Knopp - All those medicines we take to help us can sometimes be dangerous when mixed together. But now, a Seattle company has developed a Web site so we can check for ourselves if our medicines interact badly.
Can Genetic Tests Help You Lose Weight? Woman Says She Lost 40 Pounds By Following Guidelines
November 15, 2005
ABC News Denver - Can your genetic makeup help you lose weight? Some companies are offering genetic tests that they claim can tell you what you need to eat, and what not to eat, to be healthy.
A Special Drug Just for You, at the End of a Long Pipeline
November 8, 2005
The New York Times – Andrew Pollack - The age of personalized medicine is on the way. Increasingly, experts say, therapies will be tailored for patients based on their genetic makeup or other medical measurements. That will allow people to obtain drugs that would work best for them and avoid serious side effects.
Drug Cocktail, No Hangover
November 02, 2005
Wired - Michael Bradbury - Genelex offers a new online service that lets patients see how various drugs interact with one another, as well as with several gene variations that profoundly affect how drugs are processed in the liver.
Feed Your Genes: The New Science of DNA Nutrition
Outside Magazine – Adam Skolnick - We take a look at the new science of DNA nutrition - in which genetic testing tells you what to eat and how to train for peak performance.
Going from Genome to Pill
June 24, 2005
Science Magazine – Robert F. Service - A new medicine for African Americans with heart failure hints at what the drug industry sees as the enormous payoff of pharmacogenomics.
Predicting Your Body's Future
May 8, 2005
KOMO News - Kevin Beatty - What if you could see into the future to find out what problems you will face 20 or 30 years down the road and what you can do to stop it?
Labs Turn DNA Into Personal Health Forecasts
April 7, 2005
Washington Post - Ariana Eunjung Cha - The boxes arrive in the mail by the dozens each day and are stacked in neat rows in the laboratory. Inside are swabs of the inside cheek, drops of blood, material that the senders hope will give them a peek at the life they have been dealt by their genes.
A prescription to improve drug regimens?
Current Psychiatry - John Luo - One day we may be able to consistently choose medications that offer optimal benefit and minimal adverse events—without subjecting our patients to unsuccessful trials. Thanks to quantitative EEG (OEEG) testing and pharmacogenetic testing, that day may be coming closer.
Seattle's Genelex sees if the genes fit
March 1, 2005
Seattle Times - Luke Timmerman - Genelex's Howard Coleman says that with simple tests already available from companies such as his, and with sophisticated ones on the way, eventually all patients will be tested for susceptibility to a drug reaction before a doctor writes a prescription.
A Better Diet Through DNA Testing?
March 1, 2005
Wall Street Journal – Rhonda L Rundle - The field of nutrigenomics, which examines the relationship between genes and food, promises to explain why some people who gobble up cheeseburgers and french fries stay trim while others battle the bulge.
Seattle Firm Offers Personal DNA Test
Jan. 5, 2005
KIRO 7 Eyewitness News - Genelex Corporation, says its new DNA test can save the lives of 50,000 people who die every year from bad reactions to medication. Genelex says prescription medications have radically different effects in different people and by testing your DNA, they say they can predict whether a prescription drug might work for you or make you sick.
Genetic Tests May Prevent Drug Reactions
Associated Press – Gene Johnson - For most of her life, Eileen Marshall's trips to the dentist offered the prospect of sweating, itching and a racing heart. Her affliction wasn't a case of nerves before the drill. It was a genetic inability to process Novocain, something she learned last summer when she took a DNA test offered by Seattle-based Genelex Corp.
Older News Coverage
Making Medicine Safe
Reader’s Digest – Rob Waters – Several months ago, 11-year-old Hillary DeSmarais of Fort Worth, Texas, attended a party in her honor. People brought presents, laughed, and gave healthy girl hugs. It wasn’t her birthday; the party was at a hospital. At the age of six, Hillary had been diagnosed with acute lymphoblastic leukemia.
Paternity Test Clears Marc Anthony
February 2, 2004
People Magazine – Stephen Silverman – Calling their union “irretrievably broken,” former Miss Universe Dayanara Torres filed for divorce from Latin crooner Marc Anthony on Jan. 20 in Miami-Dade County, Fla., PEOPLE reports in its current issue.
Genelex diversifying its lineup of genetic tests
December 7, 2003
Puget Sound Business Journal - Heidi Dietrich - Seattle-based Genelex Corp. is trying to expand its genetic testing business with new products that examine patients' ancestry and nutritional requirements.
Firms sell Gene Tests Directly to Public
August 11, 2002
LA Times – Aaron Zitner - When a slew of medical problems hit at once, Peter Dyck found himself taking an array of drugs: three for a heart condition, one for a digestive disorder and two for other ailments. It left him wondering how his body was handling all the medications.
At Home DNA Tests are Here
June 25, 2002
Wall Street Journal – Helen Pearson – David Steene ordered a do-it-yourself home DNA test last year after reading about such kits on the Web. The results persuaded the 42-year-old London lawyer that he had a serious risk of getting cancer.
Bones identified as those of Shoreline man
January 25, 2000
Seattle Times - Mekeisha Madden - Tests taken by Genelex Laboratories in Seattle found a 99.44 percent match between DNA taken from the bones and genetic material taken from the Castillo family members.
Genetic Testing Checks For Drug Reactions
May 4, 2001
KOMO News - The Journal of the American Medical Association estimates that more than 100,000 people die in hospitals each year from adverse drug reactions. Redmond's Genelex Corp. has been doing DNA testing for years. Now it's offering a test you can do at home to see if your genes will allow your body to process certain medications.
The Upside of Antidepressants: Genetic test for adverse reaction may lift Genelex
December 17, 2000
Puget Sound Business Journal - Joel Ozretich - Genelex Corp., a Seattle-based DNA testing firm, is getting into the business of predicting adverse drug reactions, the serious and occasionally fatal side-effects some people have to common prescription drugs.
DNA labs offer new test of family ties
March 19, 2000
Associate Press - At the Genelex lab in Seattle, they like the story of Abigail and Richard. When it begins, Abigail, a 58-year-old California lawyer, has spent her whole life believing she is the only child of a politically important father, now dead. Meanwhile, Richard, a 37-year-old engineering student in Washington state, follows family rumors and contacts Abigail, telling breaking the news that she may be wrong. Much talking, investigating, and tracking down and interviewing of family friends follow. Finally, the two decide to settle the question once and for all - by DNA testing.